dc.contributor.author | Gutiérrez, Xavier Andrés | |
dc.contributor.author | Kolarevic, Jelena | |
dc.contributor.author | Takle, Harald Rune | |
dc.contributor.author | Bæverfjord, Grete | |
dc.contributor.author | Ytteborg, Elisabeth | |
dc.contributor.author | Terjesen, Bendik Fyhn | |
dc.date.accessioned | 2019-09-13T06:34:11Z | |
dc.date.available | 2019-09-13T06:34:11Z | |
dc.date.created | 2019-07-10T11:00:11Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Aquaculture Research. 2019, 50 2687-2697. | nb_NO |
dc.identifier.issn | 1355-557X | |
dc.identifier.uri | http://hdl.handle.net/11250/2616669 | |
dc.description.abstract | The present study examined the protective effects of water chloride (Cl−) towards nitrite toxicity in Atlantic salmon parr during 84‐day long nitrite exposure. Effects on growth, histology, blood indices and gene expression were studied at a fixed nominal Cl− concentration of 200 mg/L and at several water nitrite concentrations (0, 0.5, 2, 5 and 10 mg/L NO2−–N). The specific growth rate was significantly reduced during the first three weeks at a Cl:NO2−–N ratio of 21:1, suggesting the activation of coping mechanisms at the later stages of the experiment. No significant effect of nitrite on gill histology and mortality was found. Nitrite accumulated in plasma; however, a Cl:NO2−–N ratio of 104:1 or higher prevented nitrite entry. The concentration of NO2−–N in plasma was significantly reduced at the end of the study, supporting the hypothesis of coping mechanisms. Cystic fibrosis transmembrane conductance regulator (cftr)‐1 showed a significant up‐regulation at highest nitrite concentration on day 22, and in three of the highest exposure groups at the end of the experiment. Our findings suggest that a Cl:NO2−–N ratio above 104:1 should be maintained through episodes of nitrite accumulation in water during the production of Atlantic salmon parr. | |
dc.description.abstract | Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr | |
dc.language.iso | eng | nb_NO |
dc.title | Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | submittedVersion | |
dc.source.pagenumber | 2687-2697 | nb_NO |
dc.source.volume | 50 | nb_NO |
dc.source.journal | Aquaculture Research | nb_NO |
dc.identifier.doi | 10.1111/are.14226 | |
dc.identifier.cristin | 1711038 | |
dc.relation.project | Norges forskningsråd: 237856 | nb_NO |
dc.relation.project | Nofima AS: 11244 | nb_NO |
dc.relation.project | Norges forskningsråd: 186913 | nb_NO |
cristin.unitcode | 7543,1,3,0 | |
cristin.unitcode | 7543,1,5,0 | |
cristin.unitcode | 7543,1,4,0 | |
cristin.unitname | Ernæring og fôrteknologi | |
cristin.unitname | Produksjonsbiologi | |
cristin.unitname | Fiskehelse | |
cristin.ispublished | true | |
cristin.fulltext | preprint | |
cristin.qualitycode | 1 | |