Browsing NOFIMA vitenarkiv by Author "Lazado, Carlo C."
Now showing items 1-20 of 33
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Acute dose-response exposure of a peracetic acid-based disinfectant to Atlantic salmon parr reared in recirculating aquaculture systems
Mota, Vasco; Eggen, Maia L.; Lazado, Carlo C. (Peer reviewed; Journal article, 2022)There is a high regard for peracetic acid (PAA)-based disinfectants in recirculating aquaculture systems (RAS) because of the low risk of bioaccumulation, fast degradation with neutral residuals and minimal impact on ... -
Acute dose-response exposure of a peracetic acid-based disinfectant to Atlantic salmon parr reared in recirculating aquaculture systems
Mota, Vasco; Eggen, Maia L.; Lazado, Carlo C. (Peer reviewed; Journal article, 2022)There is a high regard for peracetic acid (PAA)-based disinfectants in recirculating aquaculture systems (RAS) because of the low risk of bioaccumulation, fast degradation with neutral residuals and minimal impact on ... -
Atlantic salmon (Salmo salar) mounts systemic and mucosal stress responses to peracetic acid
Soleng, Malene; Johansen, Lill-Heidi; Johnsen, Hanne; Johansson, Gunhild Seljehaug; Breiland, Mette Serine Wesmajervi; Rørmark, Lisbeth; Pittman, Karin; Pedersen, Lars-Flemming; Lazado, Carlo C. (Peer reviewed; Journal article, 2019)Peracetic acid (PAA), a strong organic peroxide, is considered a relatively sustainable disinfectant in aquaculture because of its broad effectivity against many pathogens at low concentrations and because it degrades ... -
Chemically and green synthesized ZnO nanoparticles alter key immunological molecules in common carp (Cyprinus carpio) skin mucus
Ghasem, Rashidian; Lazado, Carlo C.; Mahboub, Heba H.; Mohammadi-Aloucheh, Ramin; Prokić, Marko D.; Nada, Hend S.; Faggio, Caterina (Peer reviewed; Journal article, 2021)This study was conducted to compare the effects of commercially available (C) and green synthesized (GS) Zinc oxide nanoparticles (ZnO-NPs) on immunological responses of common carp (Cyprinus carpio) skin mucus. GS ZnO-NPs ... -
Consequences of continuous ozonation on the health and welfare of Atlantic salmon post-smolts in brackish water recirculating aquaculture system
Lazado, Carlo C.; Stiller, Kevin Torben; Reiten, Britt Kristin Megård; Osório, João; Kolarevic, Jelena; Johansen, Lill-Heidi (Peer reviewed; Journal article, 2021)This study investigated the biological consequences of 45-day continuous ozonation on Atlantic salmon (Salmo salar) post-smolts in a brackish water recirculating aquaculture system (RAS). There was no significant difference ... -
Crowding reshapes the mucosal but not the systemic response repertoires of Atlantic salmon to peracetic acid
Lazado, Carlo C.; Sveen, Lene; Soleng, Malene; Pedersen, Lars-Flemming; Timmerhaus, Gerrit (Peer reviewed; Journal article, 2021)Knowledge of the impact of aquaculture chemotherapeutants on fish physiology is scarce. This is particularly relevant for peracetic acid (PAA), a widely used oxidative disinfectant in aquaculture. The chemical behaviour ... -
Decay of peracetic acid in seawater and implications for its chemotherapeutic potential in aquaculture
Pedersen, Lars-Flemming; Lazado, Carlo C. (Peer reviewed; Journal article, 2020)Peracetic acid (PAA) is a widely applied disinfectant in aquaculture. Knowledge on PAA decay in seawater (SW) is crucial for its potential successful implementation in SW aquaculture productions systems. Furthermore, ... -
Dietary inclusion of Antarctic krill meal during the finishing feed period improves health and fillet quality of Atlantic salmon (Salmo salar L.)
Mørkøre, Turid; Moreno, Helena Maria; Borderías, Javier; Larsson, Thomas; Hellberg, Hege; Hatlen, Bjarne; Romarheim, Odd Helge; Ruyter, Bente; Lazado, Carlo C.; Jimenez Guerrero, Raul; Bjerke, Målfrid Tofteberg; Benitez-Santana, Tibiabin; Krasnov, Aleksei (Peer reviewed; Journal article, 2020) -
Dynamic morphometrics of mucous cells reveal the minimal impact of therapeutic doses of peracetic acid on Atlantic salmon gill health
Haddeland, Sindre; Lazado, Carlo C.; Merkin, Grigory; Myre, Ole Jacob; Okubamichael, Mearge; Pedersen, Lars-Flemming; Pittman, Karin (Peer reviewed; Journal article, 2021)Mucous cells, the microscopic structural hallmark of mucosal surfaces, are highly responsive to environmental changes. Here we report how the gills of Atlantic salmon (Salmo salar) responded to peracetic acid (PAA), a ... -
Evaluation of a recirculating aquaculture system research facility designed to address current knowledge needs in Atlantic salmon production
Mota, Vasco; Striberny, Anja; Verstege, Gerhardus C.; Difford, Gareth Frank; Lazado, Carlo C. (Peer reviewed; Journal article, 2022)A better understanding of recirculating aquaculture systems (RAS) biosecurity is crucial for a sustainable and ethical production of Atlantic salmon smolt and post-smolt in these systems. This study described and evaluated ... -
Exogenous sulphide donors modify the gene expression patterns of Atlantic salmon nasal leukocytes
Cabillon, Nikko Alvin; Lazado, Carlo C. (Peer reviewed; Journal article, 2021)Hydrogen sulphide (H2S) is a known mediator of immunity, but the regulatory function of its exogenous form is not well understood in fish particularly in the mucosa. Here we report transcriptomic changes in the nasal ... -
Forebyggende ernæring mot lus på laks - forsøk og dokumentasjon på betydning av samvirkning mellom aktive tilsetninger og grunnfôr. Faglig delrapport
Bogevik, André Sture; Sveen, Lene; Ytteborg, Elisabeth; Karlsen, Christian; Lazado, Carlo C.; Krasnov, Aleksei; Timmerhaus, Gerrit; Andersen, Linda; Blindheim, Steffen H.; Myre, Ole; Merkin, Grigory; Okubamichael, Mearge; Pittman, Karin (Nofima rapportserie, Research report, 2019)Aller Aqua Norway AS ble i 2017 gjennom en åpen utlysning tildelt midler fra FHF (prosjekt nr 901458) for å dokumentere effekten av mineralingrediensen Biofeed Forte (BF) mot lusesmitte på laks. Forsøk på regnbueørret ved ... -
Intermittent administration of peracetic acid is a mild environmental stressor that elicits mucosal and systemic adaptive responses from Atlantic salmon post-smolts
Osório, João; Stiller, Kevin Torben; Reiten, Britt Kristin Megård; Kolarevic, Jelena; Johansen, Lill-Heidi; Afonso, Fernando; Lazado, Carlo C. (Peer reviewed; Journal article, 2022)Background Fish encounter oxidative stress several times during their lifetime, and it has a pervasive influence on their health and welfare. One of the triggers of oxidative stress in fish farming is the use of oxidative ... -
Interplay between daily rhythmic serum-mediated bacterial killing activity and immune defence factors in rainbow trout (Oncorhynchus mykiss)
Lazado, Carlo C.; Gesto, Manuel; Madsen, Lone; Jokumsen, Alfred (Journal article; Peer reviewed, 2018)Circadian rhythm is emerging as an important regulator of immune functions. However, there is a paucity of information on the influence of this biological phenomenon in the antimicrobial factors in teleost fish. This study ... -
Mode of Application of Peracetic Acid-Based Disinfectants has a Minimal Influence on the Antioxidant Defences and Mucosal Structures of Atlantic Salmon (Salmo salar) Parr
Carletto, Danilo; Furtado, Francisco; Zhang, Junjie; Asimakopoulos, Alexandros; Eggen, Maia L.; Verstege, Gerhardus C.; Faggio, Caterina; Mota, Vasco C.; Lazado, Carlo C. (Peer reviewed; Journal article, 2022) -
Morphomolecular alterations in the skin mucosa of Atlantic salmon (Salmo salar) after exposure to peracetic acid-based disinfectant
Lazado, Carlo C.; Haddeland, Sindre; Timmerhaus, Gerrit; Berg, Ragnhild Stenberg; Merkin, Grigory; Pittman, Karin; Pedersen, Lars-Flemming (Peer reviewed; Journal article, 2020)Peroxygen-based chemotherapeutants are commonly used in treating ectoparasitic infections in fish. A majority of relevant studies address the effects of these substances on the targeted causative agents, but little is known ... -
Mucosal barrier functions of fish under changing environmental conditions
Cabillon, Nikko Alvin; Lazado, Carlo C. (Peer reviewed; Journal article, 2019)The skin, gills, and gut are the most extensively studied mucosal organs in fish. These mucosal structures provide the intimate interface between the internal and external milieus and serve as the indispensable first line ... -
Multiomics provide insights into the key molecules and pathways involved in the physiological adaptation of atlantic salmon (Salmo salar) to chemotherapeutic-induced oxidative stress
Lazado, Carlo C.; Timmerhaus, Gerrit; Breiland, Mette Serine Wesmajervi; Pittman, Karin Anna; Hytterød, Sigurd (Peer reviewed; Journal article, 2021)Although chemotherapeutics are used to treat infections in farmed fish, knowledge on how they alter host physiology is limited. Here, we elucidated the physiological consequences of repeated exposure to the potent oxidative ... -
Nytt S-CCS konsept for oppdrett av laks - Postsmoltproduksjon i FishGLOBE
Espmark, Åsa Maria Olofsdotter; Stiller, Kevin Torben; Shahzad, Khurram; Reiten, Britt Kristin Megård; Marchenko, Yuriy; Gerwins, Jascha; Radonjic, Filip Strand; Lazado, Carlo C.; Berge, Arne (Nofima rapportserie;, Research report, 2020)Denne rapporten beskriver vannkvalitet og ytelse og velferd hos post-smolt som har gått i det semilukkede anlegget FishGLOBE. I tillegg har FishGLOBE V3 og V5 blitt modellert med CFD modellering. Fire ulike caser ble ... -
Oxidant-induced modifications in the mucosal transcriptome and circulating metabolome of Atlantic salmon
Lazado, Carlo C.; Pedersen, Lars-Flemming; Kjersti, Katrine Hånes; Soleng, Malene; Breiland, Mette Serine Wesmajervi; Timmerhaus, Gerrit (Peer reviewed; Journal article, 2020)Here we report the molecular networks associated with the mucosal and systemic responses to peracetic acid (PAA), a candidate oxidative chemotherapeutic in Atlantic salmon (Salmo salar). Smolts were exposed to different ...