Blar i NOFIMA vitenarkiv på forfatter "Lazado, Carlo C."
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Sulphide donors affect the expression of mucin and sulphide detoxification genes in the mucosal organs of Atlantic salmon (Salmo salar)
Alipio, Hanna Ross; Albaladejo-Riad, Nora; Lazado, Carlo C. (Peer reviewed; Journal article, 2022)Hydrogen sulphide (H2S) is a gas that affects mucosal functions in mammals. However, its detrimental effects are less understood in fish despite being known to cause mass mortality. Here we used explant models to demonstrate ... -
Survey findings of disinfection strategies at selected Norwegian and North American land-based RAS facilities: A comparative insight
Lazado, Carlo C.; Good, Christopher (Peer reviewed; Journal article, 2021)Disinfection is an integral component of establishing effective biosecurity, through preventing pathogen introduction and transmission within and between aquaculture facilities. Nonetheless, there is a lack of documentation ... -
Temporal control of responses to chemically induced oxidative stress in the gill mucosa of Atlantic salmon (Salmo salar)
Lazado, Carlo C.; Voldvik, Vibeke (Peer reviewed; Journal article, 2020)Molecular clocks are known to mediate cellular responses during oxidative stress. This important interplay is less understood in fish, particularly at mucosal surfaces. Here we report the coordinated modulation of the ... -
The 1st International Symposium on Mucosal Health in Aquaculture – MHA2019
Lazado, Carlo C. (Journal article, 2020)The 1st International Symposium on Mucosal Health and Aquaculture (MHA2019) was held on 11–13 September 2019 in Oslo, Norway. This was the first platform of its kind that gathered people from academia, R&D institutes, and ... -
The circulating plasma metabolome of Neoparamoeba perurans-infected Atlantic salmon (Salmo salar)
Lazado, Carlo C.; Breiland, Mette Serine Wesmajervi; Furtado, Francisco; Burgerhout, Erik; Strand, David (Peer reviewed; Journal article, 2022)Metabolomics can provide insights into the dynamic small-molecule fluctuations occurring in response to infection and has become a valuable tool in studying the pathophysiology of diseases in recent years. However, its ... -
The effects of ozone on Atlantic salmon post-smolt in brackish water — Establishing welfare indicators and thresholds
Stiller, Kevin Torben; Kolarevic, Jelena; Lazado, Carlo C.; Gerwins, Jascha; Good, Christopher; Summerfelt, Steven T.; Mota, Vasco C.; Espmark, Åsa Maria Olofsdotter (Peer reviewed; Journal article, 2020)Ozone is a strong oxidant, and its use in aquaculture has been shown to improve water quality and fish health. At present, it is predominantly used in freshwater systems due to the high risk of toxic residual oxidant ... -
The optimum velocity for Atlantic salmon post-smolts in RAS is a compromise between muscle growth and fish welfare
Timmerhaus, Gerrit; Lazado, Carlo C.; Cabillon, Nikko Alvin; Reiten, Britt Kristin Megård; Johansen, Lill-Heidi (Peer reviewed; Journal article, 2021)It is increasingly common to rear Atlantic salmon smolts for longer periods in recirculating aquaculture systems (RAS) before transfer to sea cages. The conditions for this part of the life cycle are currently being ... -
The skin mucosal barrier of lumpfish (Cyclopterus lumpus L.) is weakened by exposure to potential aquaculture production related stressors
Ytteborg, Elisabeth; Lazado, Carlo C.; Noble, Christopher; Hansen, Roy-Inge; Johansen, Lill-Heidi (Peer reviewed; Journal article, 2023)Various cleaner fish species, such as the lumpfish (Cyclopterus lumpus L.), are used in the sea cage production of Atlantic salmon (Salmo salar L.) as a control measure against the ectoparasitic salmon louse (Lepeophtheirus ... -
Towards sustainable water disinfection with peracetic acid in aquaculture: A review
Liu, Dibo; Straus, David; Pedersen, Lars Flemming; Good, Christopher; Lazado, Carlo C.; Meinelt, Thomas (Peer reviewed; Journal article, 2024)eracetic acid (PAA) has a long history as an efficacious and eco-friendly disinfectant. It was first synthesised in 1902, and since then a wide range of applications has been developed in various industries. Aquaculture ... -
Transcriptome Responses of Atlantic Salmon (Salmo salar L.) to Viral and Bacterial Pathogens, Inflammation, and Stress
Krasnov, Aleksei; Johansen, Lill-Heidi; Karlsen, Christian; Sveen, Lene; Ytteborg, Elisabeth; Timmerhaus, Gerrit; Lazado, Carlo C.; Afanasyev, Sergey (Peer reviewed; Journal article, 2021)Transcriptomics provides valuable data for functional annotations of genes, the discovery of biomarkers, and quantitative assessment of responses to challenges. Meta-analysis of Nofima’s Atlantic salmon microarray database ... -
Transcriptomic landscape of Atlantic salmon (Salmo salar L.) skin
Sveen, Lene; Robinson, Nicholas Andrew; Krasnov, Aleksei; Daniels, Rose Ruiz; Vaadal, Marianne; Karlsen, Christian; Ytteborg, Elisabeth; Robledo, Diego; Salisbury, Sarah; Dagnachew, Binyam Sime; Lazado, Carlo C.; Tengs, Torstein (Peer reviewed; Journal article, 2023)In this study, we present the first spatial transcriptomic atlas of Atlantic salmon skin using the Visium Spatial Gene Expression protocol. We utilized frozen skin tissue from four distinct sites, namely the operculum, ... -
Vitamin C Mitigates Oxidative Stress and Behavioral Impairments Induced by Deltamethrin and Lead Toxicity in Zebrafish
Paduraru, Emanuela; Flocea, Elena-Iuliana; Lazado, Carlo C.; Simionov, Ira-Adeline; Nicoara, Mircea; Ciobica, Alin; Faggio, Caterina; Jijie, Roxana (Peer reviewed; Journal article, 2021)Environmental contamination from toxic metals and pesticides is an issue of great concern due to their harmful effects to human health and the ecosystems. In this framework, we assessed the adverse effects when aquatic ...