Browsing NOFIMA vitenarkiv by Author "Östman, Sofia"

Now showing items 1-2 of 2

    • pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle function 

      Philipp, Julian; Dabkowska, Aleksandra; Reiser, Anita; Frank, Kilian; Krzysztoń, Rafał; Brummer, Christiane; Nickel, Bert; Blanchet, Clement E.; Sudarsan, Akhil; Ibrahim, Mohd; Johansson, Svante; Skantze, Pia; Skantze, Urban; Östman, Sofia; Johansson, Marie; Henderson, Neil; Elvevold, Kjetil; Smedsrød, Bård; Schwierz, Nadine; Lindfors, Lennart; Rädler, Joachim O. (Peer reviewed; Journal article, 2023)
      Lipid nanoparticles (LNPs) are advanced core-shell particles for messenger RNA (mRNA) based therapies that are made of polyethylene glycol (PEG) lipid, distearoylphosphatidylcholine (DSPC), cationic ionizable lipid (CIL), ...

    • Stronger T cell immunogenicity of ovalbumin expressed intracellularly in Gram-negative than in Gram-positive bacteria 

      Martner, Anna; Östman, Sofia; Lundin, Samuel; Rask, Carola; Björnsson, Viktor; Telemo, Esbjörn; Collins, L. Vincent; Axelsson, Lars; Wold, Agnes E. (Peer reviewed; Journal article, 2013)
      This study aimed to clarify whether Gram-positive (G+) and Gram-negative (G−) bacteria affect antigen-presenting cells differently and thereby influence the immunogenicity of proteins they express. Lactobacilli, lactococci ...